A Case of Severe Leg Edema After High Intensity Focused Ultrasound Ablation for Adenomyosis: A Possible Side Effect of Gonadotrophin-Releasing Hormone Agonist Injection

Adenomyosis is a common gynecological benign disorder that deteriorates women's quality of life. The efficacy and safety of high intensity focused ultrasound (HIFU) ablation for treating adenomyosis patients has been increasingly recognized. Regardless of this fact, there are still potential adverse events thatmayhappen during and after the provision of HIFU treatment, leading to a severe adverse outcome. Patients after HIFU has always been under close observation since HFU surgery. This paper reports a sudden development of severe leg edema in a patient after HFU for adenomyosis. It mimics an urgent development of deep vein thrombosis (OVT), an urgent ultrasound scan, fortunately, excludes DVT. After exclusive investigations, the severe leg edema is found secondary to a side effect of gonadotrophin-releasing hormone agonist (GnRHa).